Directions in QSAR Modeling for Regulatory Uses in OECD Member Countries, EU and in Russia
Natalja Fjodorova, M. Novich, M. Vrachko, VJACHESLAV SMIRNOV, Nina V. Kharchevnikova, Zholdakova Zi, Novikov Sm, Natalia Alexandrovna Skvortsova, Dmitry A. Filimonov, Vladimir Poroikov, Emilio Benfenati · Journal of Environmental Science and Health Part C · 2008
The aim of this article is to show the main aspects of quantitative structure activity relationship (QSAR) modeling for regulatory purposes. We try to answer the question; what makes QSAR models suitable for regulatory uses. The article focuses on directions in QSAR modeling in European Union (EU) and Russia. Difficulties in validation models have been discussed.