Development of phenotype algorithms using electronic medical records and incorporating natural language processing

Katherine P. Liao, Tianrun A. Cai, Guergana Savova, S. N. Murphy, Elizabeth W. Karlson, Ashwin N. Ananthakrishnan, Vivian S. Gainer, Stanley Y. Shaw, Zongqi Xia, Peter Szolovits, Susanne E. Churchill, Isaac S. Kohane · BMJ · 2015

Electronic medical records are emerging as a major source of data for clinical and translational research studies, although phenotypes of interest need to be accurately defined first. This article provides an overview of how to develop a phenotype algorithm from electronic medical records, incorporating modern informatics and biostatistics methods.

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