P450-Based Nano-Bio-Sensors for Personalized Medicine
Camilla Baj-Rossi, Giovanni De, Sandro Carrar · InTech eBooks · 2011
Functional effects Most important polymorphic variants CYP1A1 Carcinogens Relatively high --CYP1A2 Drugs, carcinogens High Some CYP1A2*1F, CYP1A2*1K CYP2A6 Nicotine, drugs, carcinogens High in orientals, less frequent in Caucasians Important for nicotine metabolism CYP2A6*1B,