Dirichlet Process based model for GWAS
Govind Kothari, Avinash Das · 2012
Human population have large genetic variation. Genetic variations are usually characterized by Single Nucleotide Polymorphism (SNP). These are the location of variation in the genome sequence of two individuals. Identification of SNPs affecting human phenotype, especially leading to risks of complex disorders, is one of the key problems of medical genetics. In this project we build a probabilistic model which can determine the deleterious mutation which can lead to heart disease in humans. 1