Conformation Design of Hydrocarbon Backbones: A Modular Approach
Reinhard W. Hoffmann, Martin Ståhl, Ulrich Schopfer, Gernot Frenking · Chemistry - A European Journal · 1998
Full conformational flexibility and yet a high preference for a single backbone conformation is displayed by certain hydrocarbon skeletons such as the one on the right (calculated conformational preference >99%). The principles behind the design of such monoconformational structures are discussed here.