The Need for Precompetitive Integrative Bionetwork Disease Model Building
Stephen Henry Friend · Clinical Pharmacology & Therapeutics · 2010
If you doubt that there are enormous gaps in the current drug discovery process, you should probably skip to the next article. Yet even while critiques rightly highlight inefficiencies or operational issues, they often miss a fundamental reality: until we better understand diseases as altered bionetworks and view diseases at an individual patient level, efforts to develop effective biomarkers and therapies will be inefficient at best.