2D/3D registration of micro-CT data to multi-view photographs based on a 3D distance map

M. H. Wildeman, Martin Baiker, Johan H. C. Reiber, Clemens W.G.M. Löwik, Marcel J. T. Reinders, Boudewijn P. F. Lelieveldt · 2009

In this work we present a method for registration of a CT-derived mouse skin surface to two or more 2D, geometrically calibrated, photographs of the same animal using a similarity transformation model. We show that by using a 3D distance map, which is reconstructed from the animal skin silhouettes in the 2D photographs, and by penalizing large angle differences between distance map gradients and CT-based skin surface normals, we are able to construct a registration criterion that is robust to silhouette outliers and yields accurate results for synthetic and real data (mean skin surface distance 0.12 mm and 1.35 mm respectively).

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