Fractal Analysis of Non-Solid Pulmonary Nodules in Lung-CT Scans

Todd M. Holden, Erick H. Cheung, Avi I. Flamholz, G. Tremberger, X. Dunkley, R. Sullivan, R. Subramaniam, Patricia S. Schneider, D. Lieberman, T. Cheung · 2008

We have developed a fractal algorithm to supplement the current analysis in lung-CT scans on non-solid pulmonary nodule. The Cornell University Lung-CT Scans database and the US National Institute of Health ImageJ software were used. We found that the inner core average intensity could be a marker for the fractal dimension of a non-solid nodule. Z-scan image analysis of the adjacent boundaries showed that the fractal dimension has a range of about 0.1 in the studied cases. Extension of this proof-of-concept fractal analysis to growth rate estimation is also discussed.

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