Binary partitioning for continuous longitudinal data: categorizing a prognostic variable
Mohamed Abdolell, Michael Leo LeBlanc, Derek Stephens, Robert V. Harrison · Statistics in Medicine · 2002
We investigate a binary partitioning algorithm in the case of a continuous repeated measures outcome. The procedure is based on the use of the likelihood ratio statistic to evaluate the performance of individual splits. The procedure partitions a set of longitudinal data into two mutually exclusive groups based on an optimal split of a continuous prognostic variable. A permutation test is used to assess the level of significance associated with the optimal split, and a bootstrap confidence interval is obtained for the optimal split.