Experimental validation of in silico target predictions on synergistic protein targets
Isidro Cortés‐Ciriano, Alexios Koutsoukas, Olga Abián, Robert Charles Glen, Adrián Velázquez‐Campoy, Andreas Bender · MedChemComm · 2012
Two relatively recent trends have become apparent in current early stage drug discovery settings: firstly, a revival of phenotypic screening strategies and secondly, the increasing acceptance that some drugs work by modulating multiple targets in parallel (‘multi-target drugs’).