KI-67 hot-spots detection on glioblastoma tissue sections
Xavier Moles Lopez, Olivier Debeir, Calliope Maris, Isabelle H. Roland, Isabelle J. Salmon, Christine Decaestecker · 2010
Glioblastomas are very aggressive cerebral tumors which are characterized by strong proliferative activity which is often assessed using the Ki-67 staining method. We propose a novel clustering method that exhibits high performance to detect Ki-67 hot-spots on immunohistochemical slides of glioblastomas.