The MAPK Signal Pathway Research and New Drug Discovery
Po‐Yuan Chen, Mien-De Jhuo, Wei-Tse Hsu, Tzu‐Ching Shih, Tzu‐Hurng Cheng · 2009
MAPK cell signal transduction pathways determine the survival of the cells. If one can control this pathways, and then they will prohibit the proliferation of the cancer cells. Furthermore, they will heal the cancer smoothly. In order to attain this goal, we use lots of drugs to interact with MEK1 in MAPK, by using computer aided drug design to analyze the ligand activity of proteins in MEK1.