A New Mathematical Model for Nanotoxicology Study
Yu Han, Xiaoming Xu, Longping Yin, Shiyuan Liu · 2009
In this paper, a dynamical system model has been proposed and a new approach for analyzing homeostasis and evaluating potential systemic toxicity in a living biological system has been developed for nanotoxicology study. Based on the model and approach, the toxicity of 30 nm-sized Fe3O4nanoparticles was investigated and explained. Experiment results verify feasibility and effectiveness of the dynamical system we proposed. It also can be adapted to a wider range of applications such as general toxicology study, pharmacokinetics, efficacy and diagnosis.