Prediction of gas chromatographic relative retention times of anabolic steroids
Costas G. Georgakopoulos, O. G. Tsika, J. C. Kiburis · Analytical Chemistry · 1991
The prediction of gas chromatographic relative retention times (RRTs) of anabolic steroids, used in the doping control of athletes, was performed by a quantitative structure-retention relationship (QSRR) and multiple linear regression analysis study. A nine-variable model was generated with a multiple correlation coefficient R = 0.991 and relative standard error of less than 3%. Preliminary results indicated that the application of the model, especially in the prediction of RRTs of metabolites of the anabolic steroids, will be helpful.