More to Motion Processing
Science · 2001
Certain inherited forms of human male infertility are associated with small deletions in the long arm of the Y chromosome, which result in defective sperm production. These deletions occur most often in a genomic region called AZFc (for azoospermia factor c). The putative fertility factors encoded within AZFc are of great interest, but this region of the Y chromosome has posed an enormous challenge to conventional sequencing efforts because it is unusually rich in repetitive DNA.