Meroterpenoid MAPKAP (MK2) Inhibitors Isolated from the Indonesian Marine Sponge Acanthodendrilla sp.
David E. J. Williams, Jean‐Baptiste Telliez, Julie X. Liu, Akbar Tahir, Rob W. M. van Soest, Raymond J. Andersen · Journal of Natural Products · 2004
(+)-Makassaric acid (1) and (+)-subersic acid (2), new meroterpenoid inhibitors of the protein kinase MK2, have been isolated from the marine sponge Acanthodendrilla sp. collected in Indonesia. The structures of (+)-makassaric acid (1) and (+)-subersic acid (2) were determined by spectroscopic analysis.