Toward consistent cell segmentation: quality assessment of cell segments via appearance and geometry features
Andrew Brinker, Annika Fredrikson, Xiaofan Zhang, Richard Sourvenir, Shaoting Zhang · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · 2015
Computer-Aided Diagnosis (CAD) systems based on histopathological images rely on quality low-level image processing, including cell segmentation. Many methods for cell segmentation lack in generality and struggle with the wide variety of cell appearance and inter-cell structure present in histopathological images. We present a computationally efficient system to classify segmentation results as the first step toward automatic segment correction. This general method can applied to existing or future cell segmentation methods to provide corrections for low-quality results. Specifically, with a small collection of easy-to-compute features, we can identify incorrect segments with a high degree of accuracy, which then can be used to determine the needed corrections based on the type of segmentation failure present.