AUTOMATIC NIPPLE DETECTION IN MAMMOGRAMS USING LOCAL MAXIMUM FEATURES ALONG BREAST CONTOUR
Chun-Chu Jen, Shyr-Shen Yu · Biomedical Engineering Applications Basis and Communications · 2015
Mammogram registration is an important preprocessing technique, which helps in finding asymmetrical regions in left and right breast. However, correct nipple position is the crucial key point of mammogram registration since it is the only consistent and stable landmark upon a mammogram. To locate the nipple coordinates accurately in mammogram images, this work improves previous algorithms such as maximum height of the breast border (MHBB) and proposes a novel method consisting of local spatial-maximum mean intensity (LSMMI), local maximum zero-crossing (LMZC) based on the second-order derivative, and a combined approach dependent on LSMMI and LMZC. The proposed method is tested on 413 mammogram images from MIAS and DDSM databases. Consequently, the mean Euclidean distance (MED) between the ground truth identified by the radiologist and the detected nipple position is 0.64 cm, within 1 cm of the gold standard, for estimating the proposed method. The experimental results hence indicate that our proposed method can detect the nipple positions more accurately than other previous methods. Furthermore, the proposed select visible-nipple mammograms (SVNM) algorithm with the ability of generalization has achieved a 99% selection rate for automatic clustering of nipples in a mammography database, besides automatically detecting the breast border and nipple positions in mammograms.