On the crystallography and stereochemistry of antiepileptic drugs
A. Camerman, N. Camerman · Acta Crystallographica Section B · 1981
Prompted by investigations by the present authors into the stereochemistry of antiepileptic drugs, papers have appeared which attempt to link structural differences in benzodiazepines with differences in their anticonvulsant activities. Some of these papers have not made reference to important pharmacological data in this area and have somewhat misinterpreted the crystallographic conclusions drawn by the present authors. The present authors wish to clarify the relationship of molecular stereochemistry to anticonvulsant properties.