Using feedback to regulate gene expression in a developmental control architecture

Kester Dean Clegg, Susan Stepney, Tim Clarke · 2007

We present what we believe is the first attempt to physically reconstruct the exploratory mechanism of genetic regulatory networks. Feedback plays a crucial role during developmental processes and its mechanisms have recently become much clearer due to evidence from evolutionary developmental biology. We believe that without similar mechanisms of interaction and feedback, digital genomes cannot guide themselves across functional search spaces in a way that fully exploits a domain's resources, particularly in the complex search domains of real-world physics. Our architecture is designed to let evolution utilise feedback as part of its mechanism of exploration.

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