Uncovering negative results: Introducing an open access journal "Journal of Pharmaceutical Negative Results"

KK Mueen Ahmed, Vipra Kundoor · Pharmacognosy Magazine · 2010

Rapid determination of paeoniflorinSir, I read the recent publication on rapid determination of paeoniflorin with great interest.[1] Zhou et al. concluded that their new proposed method is a rapid, effective, binary reverse phase rapid resolution liquid chromatographic (LC) method.[1] I have some comments on this work.First, I have a concern on the cost of this new LC method.Is it expensive that prevents it from application in routine usage?Second, the quality management, especially for external quality assessment, is a problem that might prevent the generalization of this new technique.[2] Third, the LC is not the fastest technique for identification.Fluorescence-and electrochemical-based detections might be faster.

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