A compression algorithm for DNA that uses ASCII values

Priyanka, Savita Goel · 2014

The properties of DNA sequences offer an opportunity to develop DNA specific compression algorithm. A lossless two phase compression algorithm is presented for DNA sequences. In the first phase a modified version of Run Length Encoding (RLE) is applied and in the second phase the resultant genetic sequences is compressed using ASCII values. Using ASCII codes for eight bits ensures one-fourth compression irrespective of repeated or non-repeated behavior of the sequence and modified RLE technique enhances the compression further more. Not only the compression ratio of the algorithm is quite encouraging but the simple technique of compression makes it more interesting.

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