Intermolecular Accessibility: The Meaning of Molecular Connectivity
Lemont B. Kier, Lowell H. Hall · Journal of Chemical Information and Computer Sciences · 2000
The molecular connectivity indices are shown to be the numerical possibilities of a molecule encountering another identical molecule, derived from the bond accessibilites of each. The meaning of the delta values and the significance of all suppressed X-H bonds is described. A new concept of the meaning of molecular connectivity, built around bimolecular encounter accessibility, is presented.