The Influence of Age on Red Cell Diameter
ARTHUR I. SPRIGGS, R. A. Sladden · Journal of Clinical Pathology · 1958
Duringtheexamination ofstained bloodfilms fromhospital patients, theimpression was gained thattheredcells tended tobelarger inoldage thaninyoung ormiddle life. Toinvestigate this possibility, halometer readings were made on bloodfilms frompatients ofdifferent ages,and enoughevidence was collected toshowthatthere were statistically significant differences between various age groups. Thereisverylittle information abouttheeffect of age on mean redcelldiameter (M.C.D.). Saragea (1922) measured theredcell diameters of people inallthedecades ofage up to90,butsince only one personwas examined foreachdecade the results were notofmuchvalue. Price-Jones (1929) didnotdemonstrate any significant difference with age. Among100normal personsforwhom he calculated M.C.D.s, allbutfive were belowthe age of60,andallbut10were belowtheage of