Perspectives of data analysis of enzyme inhibition and activation, Part 1: Use of the three‐dimensional Km′ V′I coordinate system for data analysis of enzyme inhibition and activation
Vladimir I Krupyanko · Journal of Biochemical and Molecular Toxicology · 2009
Abstract The possibility of construction of the three‐dimensional (unfolded and folded) Km′ V′I rectangular coordinate systems convenient for vector representation of inhibited and activated enzymatic reactions as well as of a two‐dimensional Km′ V′ scalar rectangular coordinate system convenient for diagrammatic representation of enzymatic reactions is considered. The perspectives of using the properties of the three‐dimensional L vectors and their scalar L projections for data analysis of enzyme inhibition and activation are analyzed. © 2009 Wiley Periodicals, Inc. J Biochem Mol Toxicol 23:97–100, 2009; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/jbt.20273