Screening for unusual matched segments in multiple protein sequences

Joseph Naus, Ke-Ning Sheng · Communications in Statistics - Simulation and Computation · 1996

Given a sequence of i.i.d. integer valued random variables, we derive the distribution of the minimum sum of any W consecutive variables. We apply these results to evaluate the unusualness of matches (perfect or almost perfect) in multiply aligned sequences, and matches in all possible alignments of sequences.

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