A pattern recognition study of acyclic ureide anticonvulsants
Maged F. Khalil, Donald Fredric Weaver · Journal of Pharmacy and Pharmacology · 1990
A pattern recognition structure-activity study employing topological, geometric and physicochemical descriptors was performed on 27 acyclic ureide anticonvulsants. Twelve numerical descriptors were used as variables in a discriminant function analysis which categorized the ureide analogues with respect to their bioactivity. The results from the discriminant function analysis were interpreted to support a model for antiepileptic activity.