Selection of HMG-coenzyme A reductase inhibitors using multiattribute scoring tool
Azuana Ramli, Syed Mohamed Aljunid, Saperi Sulong, Faridah Aryani Mohd Yusof · BMC Public Health · 2012
Background Hypercholesterolaemia is a major risk factor for cardiovascular diseases. Treatment with HMG coenzyme A reductase inhibitors (statins) had been proven to reduce the risk. Due to high prevalence of hypercholesterolaemia, statins consumption is high. Statins available in Malaysia include atorvastatin, lovastatin, pravastatin, rosuvastatin, simvastatin and fluvastatin. All except one (fluvastatin) have piled up the MOH Drug Formulary (DF); hence the need to review the statins list. Multiattribute scoring tool (MAST) which takes into consideration all variables for rational decision making could help decision makers in reviewing the list. In this study, the six available statins were evaluated and scored.