Triple Negative Breast Cancer-An Overview and Review of Literature
Amit Gupta, Jyotika Jain, Ajay Kumar, Sunil Kumar, Neelam Wadhwa · Asian Journal of Medical Sciences · 2013
Triple-negative breast cancer refers to a specific subtype of breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or Her2/neu. About 12-17 % of ca breast have triple negative ca breast This subtype of breast cancer is clinically characterized as more aggressive and less responsive to standard treatment and associated with overall poorer prognosis. Chemotherapy is the choice of systemic therapy for triple-negative tumors. They are more susceptible to non-receptor mediated therapies than other tumors. A number of new strategies are currently being tested in clinical trials.DOI: http://dx.doi.org/10.3126/ajms.v3i2.5384 Asian Journal of Medical Sciences 3(2012) 16-20