OC006—Critical Review Of The Validation Process Of Six Predictive Biomarkers: How Good Is The Quality And Quantity Of The Evidence?
J.S. Peñataro, Neus Riba, V. Domínguez, Jorge Camarero, Xavier Carné, Gonzalo Calvo · Clinical Therapeutics · 2013
Increasing efforts have been made on the research of new predictive biomarkers in drug development, particularly in oncology. In this context, the validation process represents a difficult task with some potential methodologic limitations. In the present study, we will perform a critical review of the validation process of 6 key biomarkers in oncology.