Model-dependent noise elimination and distributed source solutions for the biomagnetic inverse problem
Andreas A. Ioannidis, Robert G. Hasson, Gerald J. Miseldine · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · 1990
Biomagnetic data are analysed with methods which do not involve point source descriptions. A vector signal transformation, previously defined, is generalised to reveal localised features at different scales in developing chick embryos in ovo. A powerful, but computationally intensive method is applied to a range of evoked MEG signals. Post-inversion temporal filtering is finally used to reveal a weak signal which seems to be generated at a surprisingly distant source. In short this work demonstrates the versatility and power of modern biomagnetic techniques in detecting, sizing and imaging the impressed current density generated by biological function in a completely non-invasive fashion.