Synthesis of 2,3‐dihydroxybenzoic acid ‐ (carboxyl‐14C)
M. G. Sundaram · Journal of Labelled Compounds and Radiopharmaceuticals · 1981
Abstract 2,3‐Dihydroxybenzoic acid‐(carboxyl‐14C) can be synthesized in high overall yield from commercially‐available 2,3‐dimethoxybenzoic acid. The synthetic route features the application of a Curtius rearrangement, the thermal decomposition of a carboxylic acid azide to an isocyanate. The method is suitable for the preparation of the title compound on both micro and semimicro scales.