Wavelet denoising of epicardial fluorescence imaging

Shien‐Fong Lin, Gustavo Kunde Rohde, Akram Aldroubi · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · 1998

High-resolution optical mapping is an emerging technique to record the activation and propagation of transmembrane potential on the surface of cardiac tissues. Important electrodynamic information previously not available from extracellular electric recording could be extracted from these detailed optical recordings. The noise contamination in the images is a major obstacle that prohibits higher level of information extraction. Because the patterns of interest contain sharp wavefronts and structures that we wish to detect and track in a series of frames, we seek to perform denoising based on wavelet decomposition approaches. Among the wavelet denoise methods that were tested in this preliminary study, the wavelet packet produced the best results that could be extended to denoise the entire image sequence for multi-dimensional information processing.

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