From azido acids to macrolactams and macrolactones
Martí Bartra, V. BOU, Jordi García, Fèlix Urpı́, Jaume Vilarrasa · Journal of the Chemical Society Chemical Communications · 1988
A new method is reported for the conversion of azido acids into lactams, via thioester formation and in situ azide reduction and cyclisation under high-dilution conditions; since the quantitative conversion of macrolactams to macrolactones has been shown to be feasible, this results in an indirect, alternative macrolactonisation procedure.