EFFECTS OF VARIOUS HORMONAL CONDITIONS IN THE INTACT RAT ON THE SYNTHESIS OF SERUM CHOLINESTERASE11
Charles H. Sawyer, John W. Everett · Endocrinology · 1946
ALTHOUGH the influence of hormones on metabolism has long been recognized, the in vivo effects of endocrine secretions on specific enzyme systems have received relatively little attention (Jensen and Tenenbaum, 1944). Only recently have endocrinologists and pharmacologists (Dempsey, 1946; Tainter et al., 1946) begun to examine hormone-enzyme relationships in their analysis of the mechanisms by which the well known terminal effects of endocrine activity are attained. The present series of papers attempts to explore this general problem, using as a starting point a sex difference observed in rats and mice with respect to an enzyme in the liver and serum.