Chemo- and bioinformatics resources for in silico drug discovery from medicinal plants beyond their traditional use: a critical review
Alexey A. Lagunin, Rajesh Kumar Goel, Dinesh Yugraj Gawande, Priynka Pahwa, Tatyana A. Gloriozova, Alexander V. Dmitriev, Sergey M. Ivanov, Anastasia V. Rudik, V. Konova, Pavel V. Pogodin, Dmitry Druzhilovsky, Vladimir Poroikov · Natural Product Reports · 2014
In silico approaches have been widely recognised to be useful for drug discovery. Here, we consider the significance of available databases of medicinal plants and chemo- and bioinformatics tools for in silico drug discovery beyond the traditional use of folk medicines. This review contains a practical example of the application of combined chemo- and bioinformatics methods to study pleiotropic therapeutic effects (known and novel) of 50 medicinal plants from Traditional Indian Medicine.