Digital processing of histopathological aspects in renal transplantation

Arnaldo de Albuquerque Araújo, Marcos Carneiro de Andrade, Eduardo Alves Bambirra, A. M. M. dos Santos · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · 1993

We describe here our initial experience with the digital image processing of histopathological aspects from multiple renal biopsies of transplanted kidney in a patient treated with Cyclosporine (CsA), a powerful immunosupressor drug whose use has improved the chances of a successful vascularized organ transplantation (Tx). Unfortunately, CsA promotes morphological alterations to the glomerular structure of the kidneys. To characterize this process, glomeruli, tufts, and lumen areas distributions are measured. The results are presented in form of graphics.

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