Alzheimers Disease: Targets For Drug Development

Andrew J. Larner · Mini-Reviews in Medicinal Chemistry · 2002

The numerous advances in the understanding of the neurobiology of Alzheimers disease in the past 15 years have suggested many new potential targets for therapeutic intervention. This article gives a broad overview of the spectrum of targets for AD treatment, with particular emphasis on amyloid β-peptides and tau protein. Keywords: Alzheimers Disease, Amyloid Plaques, Tau Phosphorylation Inhibitors, Tau Aggregation Blockers, GLIAL CELLS

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