QSAR-guided semi-synthesis and in vitro validation of antiplasmodial activity in ursolic acid derivatives
Komal Kalani, Harveer Singh Cheema, Himanshu Tripathi, Feroz Khan, M. P. Daroker, Santosh K. Srivastava · RSC Advances · 2015
As a part of antimalarial drug discovery programme, a QSAR model was developed for the prediction of antiplasmodial activity in ursolic acid derivatives, followed by semi-synthesis of virtually active derivatives and their biological evaluation.