Ligand-Based Drug Design Methodologies in Drug Discovery Process: An Overview
Magdalena Bacilieri, Stefano Moro · Current Drug Discovery Technologies · 2006
Ligand-based drug design represents an important research field in the drug discovery and optimisation process. This review provides an overview about the theoretical background of the quantitative structure activity relationship (QSAR) models. Keywords: Ligand-based drug design, chemometrics, quantitative structure-activity relationship (QSAR), drug discovery