Evaluation of Homology Modeling of the Severe Acute Respiratory Syndrome (SARS) Coronavirus Main Protease for Structure Based Drug Design
Mayuko Takeda‐Shitaka, Hiroyuki Nojima, Daisuke Takaya, Kazuhiko Kanou, Mitsuo Iwadate, Hideaki Umeyama · Chemical and Pharmaceutical Bulletin · 2004
To accelerate the development of drugs against severe acute respiratory syndrome (SARS), we constructed a homology model of the SARS coronavirus main protease using our modeling software, FAMS Ligand&Complex, and released it before the X-ray structure was solved. The X-ray structure showed our model as accurately predicted and useful for structure based drug design.