Relationship between magnification and resolution in digital pathology systems

Tiffany L. Sellaro, Robert J. Filkins, Chelsea Hoffman, Jeffrey L. Fine, Jon Ho, Anil Vasdev Parwani, Liron Pantanowitz, Michael Montalto · Journal of Pathology Informatics · 2013

Many pathology laboratories are implementing digital pathology systems. The image resolution and scanning (digitization) magnification can vary greatly between these digital pathology systems. In addition, when digital images are compared with viewing images using a microscope, the cellular features can vary in size. This article highlights differences in magnification and resolution between the conventional microscopes and the digital pathology systems. As more pathologists adopt digital pathology, it is important that they understand these differences and how they ultimately translate into what the pathologist can see and how this may impact their overall viewing experience.

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