Tracking multiple interacting subcellular structure by sequential Monte Carlo method

Quan Wen, Katherine Luby‐Phelps, Jean Gao · International Journal of Data Mining and Bioinformatics · 2009

With the wide application of Green Fluorescent Proteins (GFP) in the study of live cells, there is a surging need for computer-aided analysis on the huge amount of image sequence data acquired by the advanced microscopy devices. In this paper, a framework based on Sequential Monte Carlo (SMC) is proposed for multiple interacting object tracking. The distribution of the dimension varying joint state is sampled efficiently by a Reversible Jump Markov Chain Monte Carlo (RJMCMC) algorithm with a novel height swap move. Experimental results were performed on synthetic and real confocal microscopy image sequences.

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