Opportunity Knocks: Organic Chemistry for Fragment‐Based Drug Discovery (FBDD)
Christopher W. Murray, David C. Rees · Angewandte Chemie International Edition · 2015
What’s a good fragment? Fragment-based drug discovery is well-established within many pharmaceutical, biotech, and academic institutions for generating new drugs. In this Essay, the opportunities and challenges for organic chemists to design and synthesize new fragments are described.