Stochastic Programming on Optimal Drug Administration for Three-Stage Cancer Chemotherapy Treatment
P. Tirupathi Rao, Bindey Kumar, P. R. S. Reddy · American Journal of Operational Research · 2013
In this paper, a stochastic programming problem is formu lated for optimal d rug administration to the cancer patients under chemotherapy. A stochastic model for three-stage cancer growth(1) has been considered for formulating the objective function and constraints. The objective of the problem is to maximize the drug efficacy subject to the constraints on the admissible protocols of healthy drug admin istration. The health status of the patient during drug presence and its absence can be evaluated through the developed model. Nu merical illustrations were g iven for better understanding the model. Th is study will have extensive uses for health care industry in optimal chemotherapy.