Similarity of molecular electrostatic potential distributions in a series of HMG-CoA inhibitors
Ugo Cosentino, Laura Bonati, Giorgio Moro, Marina Lasagni, Demetrio Pitea · AIP conference proceedings · 1991
A methodology based on molecular modeling and chemometrics [1] has been applied for the identification of the geometrical pharmacophore in a series of inhibitors of HMG‐CoA, an enzyme involved in cholesterol biosynthesis.