The Molecular Basis of Predicting Druggability
Bissan Al‐Lazikani, Anna Gaulton, Gaia Valeria Paolini, Jerry Lanfear, John P. Overington, Andrew L. Hopkins · 2007
10.1002/9783527619368.ch36.abs This chapter contains sections titled: Introduction Chemical Properties of Drugs, Leads and Tools Molecular Recognition is the Basis for Druggability Estimating the Size of the Druggable Genome Homology-based Analysis of Drug Targets Feature-based Druggability Prediction Structure-based Druggability Analysis of Protein Data Base (PDB) Structures How Many Drug Targets are Accessible to Protein Therapeutics? Conclusions References