Prediction of Log P with Substructure‐Based Methods
Raimund Mannhold, Claude Ostermann · Methods and principles in medicinal chemistry · 2007
This chapter contains sections titled: Introduction Fragmental Methods Σf System KLOGP KOWWIN CLOGP Fragmentation Rules Structural Factors Interaction Factors: Aliphatic Proximity Interaction Factors: Electronic Effects through π-Bonds Interaction Factors: Special Ortho Effects ACD/LogP AB/LogP Atom-based Methods Ghose–Crippen Approach XLOGP Predictive Power of Substructure-based Approaches