High‐Throughput Workflow Development: Strategies and Examples in Heterogeneous Catalysis
H. Sam Bergh · 2004
This chapter contains sections titled: Introduction High-Throughput Methods DOE – Designing Experiments Based on Statistics Constrained Optimization – Independent Variables Constrained Optimization – Dependent Variables Methods to Include Synthesis Hardware Constraints Process Simulation for Hardware Bottleneck Identification Workflow Components Primary Synthesis Primary Synthesis: Wafer-based Sol-gel and Evaporative Synthesis Primary Synthesis: Wafer-based Impregnation Synthesis Primary Screening: Scanning Mass Spectrometer Primary Screening: Massively Parallel Microfluidic Reactor Secondary Synthesis: Bulk Impregnation Secondary Synthesis: Bulk Evaporation/Precipitation Secondary Synthesis: Hydrothermal Secondary Screening: 48-Channel Fixed-bed Reactor High-Throughput Catalyst Characterization Tertiary Screening Example: Ethane to Ethylene Example: Ethane to Acetic Acid Example: Propane to Acrylonitrile Summary References