SUBSARCOLEMMAL STRUCTURE OF CARDIOMYOCYTES OF PATIENTS WITH MITRAL VALVE DEFECT AND CORONARY ARTERIA DISEASE
N. S. Kukurtchyan, Gevorg Karapetyan · European Chemical Bulletin · 2013
Understanding of the mechanisms lying in the changes of the CMC subsarcolemmas (SS) will give opportunities for searching the medicaments assuring maximal protection of cells. In this study, for the first time, we demonstrated CAD and MVD influence on the myocardium leading to the alterations of CMC SS cytoskeleton thickness. The alterations of SS structures as well as in mitochondria of cells could be one of the main reasons leading to postsurgical damages of cardiomyocytes.